|
| Status |
Public on Jan 25, 2012 |
| Title |
mRNA profiles of four developmentally related hematopoietic cell types (LSK, L-S-K+, Gr1+ and Ter119+) isolated from the BM of B6 and D2 mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The combination of valproic acid and lithium delays hematopoietic stem\progenitor differentiation
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| Overall design |
Microarray-based microRNA profiling study was peformed of four developmentally related hematopoietic cell types isolated from the BM of B6 and D2 mice. Total RNA isolated from purified LSK multilineage cells, committed LS−K+ cells, erythroid TER-119+ cells and myeloid Gr-1+ cells was hybridized to Single Color Illumina mouse WG-6_V2 mRNA arrays. Triplicates were generated for each of the 8 conditions (4 cell types, 2 mouse strains).
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| |
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| Contributor(s) |
Walasek MA, Bystrykh LV, van den Boom V, Olthof S, Ausema A, Ritsema M, Huls G, de Haan G, van Os R |
| Citation(s) |
22327222 |
| Submission date |
Jan 24, 2012 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Leonid Bystrykh |
| E-mail(s) |
l.bystrykh@umcg.nl
|
| Organization name |
University Medical Center Groningen
|
| Department |
European Research Institute for the Biology of Ageing - ERIBA
|
| Lab |
Ageing Biology and Stem Cells
|
| Street address |
A. Deusinglaan 1
|
| City |
Groningen |
| State/province |
Groningen |
| ZIP/Postal code |
9713 AV |
| Country |
Netherlands |
| |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
|
| Samples (24)
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| This SubSeries is part of SuperSeries: |
| GSE34088 |
The combination of valproic acid and lithium prevents hematopoietic stem/progenitor cell differentiation. |
|
| Relations |
| BioProject |
PRJNA156023 |
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