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Series GSE35676 Query DataSets for GSE35676
Status Public on Mar 14, 2012
Title eQTL study of bone marrow derived macrophages and endothelial cells from DBA2xAKR F2 mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary An eQTL analysis between DBA/2J and AKR/J mice strains on the ApoE null background was done in bone marrow derived macrophages and endothelial cells to identify modifier genes that affect atherosclerosis susceptibility.
Overall design DBA/2J mice were crossed with AKR/J mice and their offspring crossed with each other to yield an F2 generation. Bone marrow derived macrophages were cultured and gene expression quantified using Illumina's MouseRef-8 v2 arrays in 170 F2 mice for an eQTL study. In addition primary endothelial cells derived from the aorta of 48 male F2 mice were also assayed using arrays for eQTL mapping. Lesion area in the aortic root was also quantified in these samples.
Contributor(s) Hsu J, Smith JD
Citation(s) 23525445
Submission date Feb 09, 2012
Last update date Jun 14, 2018
Contact name Jeff Hsu
Phone 2162443723
Organization name Cleveland Clinic Lerner Research Institute
Department Cellular and Molecular Medicine
Lab Smith
Street address 9500 Euclid Ave
City Cleveland
State/province OH
ZIP/Postal code 44195
Country USA
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (218)
GSM872020 ECC_F2A_24_M
GSM872021 ECC_F2A_1_M
GSM872022 ECC_F2A_3_M
BioProject PRJNA152451

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE35676_RAW.tar 3.1 Mb (http)(custom) TAR
GSE35676_genotypes.txt.gz 19.8 Kb (ftp)(http) TXT
Raw data included within Sample table
Processed data included within Sample table
Processed data are available on Series record

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