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Series GSE360 Query DataSets for GSE360
Status Public on Mar 26, 2003
Title Macrophages and dendritic cells exposed to phylogenetically distinct parasites
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Monocyte-derived dendritic cells (DC) and macrophages (MΦ) generated in vitro from the same individual blood donors were exposed to five different pathogens, and gene expression profiles were assessed by microarray analysis. Responses to Mycobacterium tuberculosis and to phylogenetically distinct protozoan (Leishmania major, L. donovani, Toxoplasma gondii) and helminth (Brugia malayi) parasites were examined, each of which produces chronic infections in humans yet vary considerably in the nature of the immune responses they trigger.
Keywords: equivalent probe
 
 
Contributor(s) Chaussabel D, Semnani RT, McDowell MA, Sacks D, Sher A, Nutman TB
Citation(s) 12663451
Submission date Mar 26, 2003
Last update date Dec 13, 2018
Contact name Damien Chaussabel
E-mail(s) DChaussabel@benaroyaresearch.org
Organization name Baylor Institute for Immunology Research
Street address 3434 Live Oak
City Dallas
State/province TX
ZIP/Postal code 75204
Country USA
 
Platforms (1)
GPL8300 [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Samples (28)
GSM5123 Dendritic Cells, Baseline - Repeat #1
GSM5125 Dendritic Cells, Exposed to Leishmania donovani - Repeat #1
GSM5128 Dendritic Cells, Exposed to Leishmania major - Repeat #1
Relations
BioProject PRJNA84853

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Supplementary data files not provided

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