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Series GSE36307 Query DataSets for GSE36307
Status Public on Mar 06, 2012
Title Gene expression in liver of wild-type and Dicer1-KO mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea
Organism Mus musculus
Experiment type Expression profiling by array
Summary To explore the possible changes of gene expression induced by a carcinogen, we treated wild-type and Dicer1-KO mice with one dose of 120 mg/kg N-ethyl-N-nitrosourea (ENU), a model genotoxic carcinogen, and vehicle control. The gene expression profiles were assessed in the mouse livers in wild-type and Dicer1-KO mice design. Total RNA were isolated from the livers at days 15 after the treatment and their expression was determined using Gene Array.
 
Overall design Gene expression in treated wild-type and Dicer1-KO mice was measured at 15 days after exposure to one dose of 120 mg/kg N-ethyl-N-nitrosourea (ENU). Each treatment duplex ,Drug-ko-a,Drug-ko-b,Drug-wt-a,Drug-wt-b,Control-ko-a,Control-ko-b,Control-wt-a,Control-wt-b.
 
Contributor(s) Yang L, Qi X, Xu L
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Submission date Mar 06, 2012
Last update date May 10, 2018
Contact name Luan Yang
E-mail(s) yluan@cdser.simm.ac.cn
Phone 021-38770863
Organization name Shanghai Institute of Medicine of Chinese Academy of Medical Sciences
Street address 555 Zu Chong Zhi Road , Zhang Jiang Hi-Tech Park, Pudong, Shanghai
City shanghai
ZIP/Postal code 201203
Country China
 
Platforms (1)
GPL4134 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version)
Samples (8)
GSM886763 Drug-ko-a
GSM886764 Drug-ko-b
GSM886765 Drug-wt-a
Relations
BioProject PRJNA153055

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36307_Differential_Expression_datasheet.xls.gz 4.4 Mb (ftp)(http) XLS
GSE36307_RAW.tar 70.1 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
Processed data provided as supplementary file

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