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Series GSE36407 Query DataSets for GSE36407
Status Public on Mar 15, 2013
Title mRNA Expression data from transverse aortic constriction hearts (cardiovascular disease) and sham hearts in mice.
Organism Mus musculus
Experiment type Expression profiling by array
Summary We used transverse aortic constraction pressure overload hypertrophy mouse hearts as a model of cardiovascular disease to study the genetic changes between TAC and SHAM (normal) mouse hearts and over 1 circadian cycle (24h). This is one approach to identify diurnal genetic biomarkers of cardiovascular disease.
The micorarray approach allowed to see the gene expression in all genes in cardiovascular disease and sham hearts.
 
Overall design There are 36 samples of cardiovascular disease (TAC) and normal SHAM hearts. For TAC: There were 3 mice sacrificed at each time point as biological replicates, for 6 timepoints over 24 hrs. For SHAM: There were 3 mice sacrificed at each time point as biological replicates, for 6 timepoints over 24 hrs.
 
Contributor(s) Martino TA, Tsimakouridze EV
Citation(s) 22823865, 24789993
Submission date Mar 09, 2012
Last update date Jan 08, 2019
Contact name Elena Tsimakouridze
E-mail(s) etsimako@uoguelph.ca
Organization name University of Guelph
Street address 50 Stone Rd E
City Guelph
ZIP/Postal code N1G 2W1
Country Canada
 
Platforms (1)
GPL339 [MOE430A] Affymetrix Mouse Expression 430A Array
Samples (36)
GSM892482 SHAM at ZT23, biological rep1
GSM892483 SHAM at ZT03, biological rep1
GSM892484 SHAM at ZT07, biological rep1
Relations
BioProject PRJNA153205

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36407_RAW.tar 342.2 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
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