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Series GSE36633 Query DataSets for GSE36633
Status Public on Mar 21, 2012
Title Analysis of differential genetic expression by dietary intervention using moderate-carbohydrate restriction diet supplemented with calorie restriction mimetic multiple phytochemicals extracts(MCDmp) in B16F10 xenografted mouse model.
Organism Mus musculus
Experiment type Expression profiling by array
Genome binding/occupancy profiling by genome tiling array
Summary We performed survival analysis of control and MCDmp groups, and explored underlying tumor suppression mechanisms after dietary intervention, focused on alterations in the energy-dependent signaling pathways, and global gene expression differences on cDNA microarray study, or histone modification on ChIP-on-chip analysis.
 
Overall design Illumina arrays: Five- week- old male C57BL6 mice were randomly divided into two groups and fed control diet (control group, LabDiet, Brentwood, MO, USA) or MCDmp formula (Treat group) in a specific pathogen free zone. All procedures were approved by the institutional animal use and care committee. Following a preliminary feeding of each diet formula for one week, 1 × 106 B16F10 cells (suspended with 100 μl of PBS) were subcutaneously injected into the back of the mice. After 24 days of diet supplementation, all mice were sacrificed. Tumor tissue was excised for cDNA microarray.
 
Contributor(s) Lee JD, Choi M
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Submission date Mar 20, 2012
Last update date Jun 14, 2018
Contact name Jong-Doo Lee
E-mail(s) JDLEE@yuhs.ac
Phone 82-10-2829-1159
Fax 82-2-312-0578
Organization name Yonsei University
Street address 250 seonsan-ro seodaemum-gu
City Seoul
ZIP/Postal code 120-752
Country South Korea
 
Platforms (2)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
GPL7099 Agilent-015279 Mouse CpG Island ChIP-on-Chip Microarray 2x105K (Feature Number version)
Samples (19)
GSM897743 Control Diet Supplemented Mouse 1
GSM897744 Control Diet Supplemented Mouse 2
GSM897745 Control Diet Supplemented Mouse 3
Relations
BioProject PRJNA153631

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36633_RAW.tar 150.1 Mb (http)(custom) TAR (of TXT)
GSE36633_non-normalized.txt.gz 2.1 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record
Raw data provided as supplementary file
Processed data provided as supplementary file

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