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| Status |
Public on Mar 23, 2012 |
| Title |
Gene profiling in mucosal biopsies of Eosinophilic Esophagitis patients pre and post glucocorticoid steroid treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the gene expression changes in EoE before and after a successful glucocorticoid steroid treatment.
We used microarrays to identify distinct genes involving the pathophysiology of EoE.
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| Overall design |
Esophageal mRNA from the epithelial layers of 5 paired paraffin-embedded biopsies before and after treatment with glucocorticosteroids were harvested and profiled using Affymetrix Human Gene 1.0 ST array to generate differentially regulated mRNA transcripts.
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| Contributor(s) |
Lu S, Cleveland K, Schorl C, Mukkada VA, Resnick MB |
| Citation(s) |
22815788 |
| Submission date |
Mar 22, 2012 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Shaolei Lu |
| E-mail(s) |
slu@lifespan.org
|
| Phone |
401-444-5709
|
| Organization name |
Rhode Island Hospital
|
| Department |
Pathology
|
| Street address |
593 Eddy Steet
|
| City |
Providence |
| State/province |
Rhode Island |
| ZIP/Postal code |
02903 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE36727 |
MicroRNA Profiling in Mucosal Biopsies of Eosinophilic Esophagitis Patients Pre and Post Glucocorticoid Steroid Treatment and Relationship with mRNA Target Expression |
|
| Relations |
| BioProject |
PRJNA155461 |
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