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Status |
Public on Sep 01, 2012 |
Title |
In vivo and in vitro investigations of heterozygous nebulin knock-out mice reveal similarities with mild human form of nemaline myopathy [miRNA] |
Platform organism |
synthetic construct |
Sample organism |
Mus musculus |
Experiment type |
Non-coding RNA profiling by array
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Summary |
In the present study, we used a multimodal approach including protein and gene expression analysis and combined in vivo and in vitro measurements of force production. Overall, we aimed at investigating the functional impact of the expression of a single nebulin allele.
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Overall design |
Comparison of the miRNA expression profile of quadriceps in 3 nebulin wild type mice with 3 nebulin heterozygous mice.
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Contributor(s) |
Gineste C, De Winter J, Kohl CH |
Citation missing |
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Submission date |
Mar 23, 2012 |
Last update date |
May 02, 2017 |
Contact name |
Carsten Sticht |
Organization name |
University Heidelberg
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Department |
ZMF
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Street address |
Theodor-Kutzer-Ufer
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City |
Mannheim |
ZIP/Postal code |
68169 |
Country |
Germany |
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Platforms (1) |
GPL8786 |
[miRNA-1] Affymetrix Multispecies miRNA-1 Array |
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Samples (6)
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This SubSeries is part of SuperSeries: |
GSE36745 |
In vivo and in vitro investigations of heterozygous nebulin knock-out mice reveal similarities with mild human form of nemaline myopathy |
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Relations |
BioProject |
PRJNA155437 |