|
| Status |
Public on May 01, 2013 |
| Title |
Expression profile of the endocrine therapy resistant breast cancer cells LTED depleted of PBX1 or treated with the gamma-secretase inhibitor MRK003 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of the response to PBX1 deprivation either using an siRNA approach or using a chemicalcompound indirectly targeting it. Deprivation of PBX1 is hypothesized to be essential for the growth of endocrine therapy resistant breast cancer cells (LTED)
|
| |
|
| Overall design |
Total RNA was obtained from cells treated with siPBX1 or a control siRNA. The second set contains RNA from cells treated with MRK003 or a control (DMSO).
|
| |
|
| Contributor(s) |
Magnani L |
| Citation(s) |
23576735 |
| Submission date |
Mar 29, 2012 |
| Last update date |
Aug 13, 2018 |
| Contact name |
luca magnani |
| E-mail(s) |
luca.magnani@dartmouth.edu
|
| Phone |
6036539932
|
| Fax |
6036539952
|
| Organization name |
Dartmouth College
|
| Department |
Genetics
|
| Lab |
Lupien
|
| Street address |
NCCC one medical drive
|
| City |
Lebanon |
| State/province |
NH |
| ZIP/Postal code |
03756 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (12)
|
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| This SubSeries is part of SuperSeries: |
| GSE39418 |
Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer |
|
| Relations |
| BioProject |
PRJNA157103 |
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