|
| Status |
Public on Apr 09, 2013 |
| Title |
Portrait of early-onset breast cancer in Brazilian patients: germline mutation screening of BRCA1, BRCA2 and TP53 genes and tumor expression profiling |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Differentially expressed genes between BRCA1/BRCA2 negative and positive mutation driven-tumors.
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| |
|
| Overall design |
Screening for germline mutations was performed in a cohort of 55 patients under the age of 35 years in the BRCA1, BRCA2, CHEK2 (c.del1,100C) and TP53 genes, and the respective tumors were investigated regarding hormonal receptors status, HER2 expression. Transcriptional profiles were performed using Agilent one color hybridizations in a G4112F platform.
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| |
|
| Contributor(s) |
Carraro DM, Brentani MM |
| Citation(s) |
23469205, 25006670 |
| Submission date |
Apr 09, 2012 |
| Last update date |
Jul 24, 2019 |
| Contact name |
Renato David Puga |
| Organization name |
Universidade de São Paulo
|
| Department |
Instituto de Psiquiatria
|
| Lab |
Laboratório de Genética
|
| Street address |
Dr Ovidio Pires de Campos,785
|
| City |
São Paulo |
| State/province |
São Paulo |
| ZIP/Postal code |
05403-010 |
| Country |
Brazil |
| |
|
| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
|
| Samples (49)
|
|
| Relations |
| BioProject |
PRJNA158299 |
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