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Status |
Public on May 10, 2013 |
Title |
Genome-wide analysis of gene expression in adipose tissue of female mice after continuous high fat diet feeding |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Analysis of gene expression in adipose tissue of female mice after continuous high fat diet (HFD) feeding for three generations. The hypothesis in this study is that continuous HFD feeding has transgenerational amplification effects to the offspring. Results provide important information on the impacts of over-nutrition over one generation on the offspring, such as transgenerational up-regulated or down-regulated genes.
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Overall design |
Total RNA was obtained from adipose tissue of the HFD fed mice, including F0, F1 and F2 generations. Normal chow fed mice were used as controls.
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Contributor(s) |
Ding Y, Zheng L |
Citation(s) |
23736364 |
Submission date |
Apr 12, 2012 |
Last update date |
Jan 16, 2019 |
Contact name |
Ling Zheng |
E-mail(s) |
lzheng@whu.edu.cn, ywding0628@gmail.com
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Phone |
86-27-6875-5559
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Organization name |
Wuhan University
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Department |
College of Life Science
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Lab |
4103 Lab
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Street address |
Wuhan University
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City |
Wuhan |
ZIP/Postal code |
430072 |
Country |
China |
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Platforms (1) |
GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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Samples (4)
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GSM914143 |
white adipose_normal chow_9months_mix3 |
GSM914144 |
white adipose_HFD F0_9months_mix4 |
GSM914145 |
white adipose_HFD F1_9months_mix4 |
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Relations |
BioProject |
PRJNA158967 |