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Status |
Public on Jun 18, 2012 |
Title |
Gene expression analysis of developing limbs |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
To evaluate geneexpression profile in developing joints vs adjacent growth plate in control and TGF-beta type II receptor conditional knock-out in limb mesenchyjme
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Overall design |
We obtained E14.5 autopods from two normal controls and two Tgfbr2Prx1KO littermate embryos. Samples were frozen in OTC and cryosectioned and subjected to laser-capture microdissection for RNA sampling for interzone, growth plate chondrocytes and interdigital tissue. RNas were subjected to microarray analysis
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Contributor(s) |
Longobardi L, Spagnoli A, O'Rear L |
Citation missing |
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Submission date |
Apr 16, 2012 |
Last update date |
May 10, 2018 |
Contact name |
Anna Spagnoli |
E-mail(s) |
spagnoa@med.unc.edu
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Phone |
9198436904
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Fax |
9198436908
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Organization name |
University of North Carolina at Chapel Hill
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Department |
Pediatrics
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Street address |
103 Mason Farm Road
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City |
Chapel Hill |
State/province |
NC |
ZIP/Postal code |
27599 |
Country |
USA |
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Platforms (1) |
GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
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Samples (6)
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GSM915639 |
Interzone Tgfbr2Prx1KO mutants |
GSM915640 |
Growth Plate Chondrocyte Tgfbr2Prx1KO mutants |
GSM915641 |
Interdigital Tissue Tbr2Prx1KO mutants |
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Relations |
BioProject |
PRJNA159407 |