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| Status |
Public on Jan 01, 2013 |
| Title |
Genome-wide expression profiling analysis of a Sphingomyelin Synthase 1 mutant mouse model |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Lysosomal storage diseases are congenital lipid metabolism disorders, often accompaning by male infertility. Sms1, the enzyme, that generates sphingomyelin from ceramides seems to be involved in spermatogeneis and spermiogenesis. Therefore, testis but also muscle and brain of a mouse line carrying an insertional mutation in Sms1 were analysed.
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| Overall design |
Total RNA obtained from 4 male mutant mice was compared to four wild type controls.
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| Contributor(s) |
Beckers J, Horsch M, Floss T, Wittmann A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 17, 2012 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Martin Irmler |
| Organization name |
Helmholtz Zentrum München GmbH
|
| Department |
Institute of Experimental Genetics
|
| Lab |
Gene Regulation & Epigenetics
|
| Street address |
Ingolstaedter Landstrasse 1
|
| City |
Neuherberg |
| State/province |
Bayern |
| ZIP/Postal code |
85764 |
| Country |
Germany |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (22)
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| Relations |
| BioProject |
PRJNA159903 |
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