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Series GSE37359 Query DataSets for GSE37359
Status Public on Jan 01, 2013
Title Genome-wide expression profiling analysis of a Sphingomyelin Synthase 1 mutant mouse model
Organism Mus musculus
Experiment type Expression profiling by array
Summary Lysosomal storage diseases are congenital lipid metabolism disorders, often accompaning by male infertility. Sms1, the enzyme, that generates sphingomyelin from ceramides seems to be involved in spermatogeneis and spermiogenesis. Therefore, testis but also muscle and brain of a mouse line carrying an insertional mutation in Sms1 were analysed.
Overall design Total RNA obtained from 4 male mutant mice was compared to four wild type controls.
Contributor(s) Beckers J, Horsch M, Floss T, Wittmann A
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Submission date Apr 17, 2012
Last update date Jun 14, 2018
Contact name Martin Irmler
Organization name Helmholtz Zentrum M√ľnchen GmbH
Department Institute of Experimental Genetics
Lab Gene Regulation & Epigenetics
Street address Ingolstaedter Landstrasse 1
City Neuherberg
State/province Bayern
ZIP/Postal code 85764
Country Germany
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (22)
GSM916654 testis_wt_rep1
GSM916655 testis_wt_rep2
GSM916656 testis_wt_rep3
BioProject PRJNA159903

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE37359_RAW.tar 3.1 Mb (http)(custom) TAR
GSE37359_non-normalized_data.txt.gz 3.4 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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