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Series GSE37611 Query DataSets for GSE37611
Status Public on Nov 03, 2012
Title Effect of small molecules on activated astrocytes
Organism Mus musculus
Experiment type Expression profiling by array
Summary We have developed an assay to test the neuroprotective properties of compounds using stem cell–derived motor neurons and astrocytes, together with activated microglia as a stress paradigm.
Hit compounds were discovered and the transcriptional response on activated astrocytes cells was tested.
 
Overall design Neural stem cell (NSC)-derived astrocytes (AC) were activated with LPS and IFN-γ and treated with hit compound for 4 hr.
 
Citation(s) 23064101
Submission date Apr 26, 2012
Last update date Jun 14, 2018
Contact name Susanne Höing
E-mail(s) s.hoeing@mpi-muenster.mpg.de
Organization name Max Planck Institute for Molecular Biomedicine
Department Cell and Developmental Biology
Street address Röntgenstraße 20
City Münster
ZIP/Postal code 48149
Country Germany
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (12)
GSM923212 AC_non-activated control
GSM923213 AC_activated control
GSM923214 AC_E4
This SubSeries is part of SuperSeries:
GSE37613 Effect of small molecules on activated astrocytes and microglia cells
Relations
BioProject PRJNA162319

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE37611_RAW.tar 3.1 Mb (http)(custom) TAR
GSE37611_non_normalized_AC.txt.gz 1.9 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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