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| Status |
Public on Aug 16, 2012 |
| Title |
Testis Gene Expression Changes after JQ1 treatment |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
JQ1 is a small-molecule (BET family) bromodomain inhibitor that causes a contraceptive effect in mice by blocking spermatogenesis and reducing sperm motility.
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| Overall design |
Genome-wide Illumina gene expression analysis of male mice treated with 50 mg/kg JQ1(treated) or vehicle (control) daily for 6 weeks (6-12 weeks of age).
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| Contributor(s) |
Matzuk MM, McKeown MR, Filippakopoulos P, Li Q, Ma L, Agno JE, Lemieux ME, Picaud S, Yu RN, Qi J, Knapp S, Bradner JE |
| Citation(s) |
22901802 |
| Submission date |
May 10, 2012 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Qinglei Li |
| E-mail(s) |
qli@cvm.tamu.edu
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| Organization name |
Texas A&M University
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| Street address |
4458 TAMU
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| City |
College Station |
| State/province |
TX |
| ZIP/Postal code |
77843 |
| Country |
USA |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA165127 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE37894_RAW.tar |
15.8 Mb |
(http)(custom) |
TAR |
| GSE37894_non-normalized_data.txt.gz |
1.2 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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