|
| Status |
Public on May 22, 2013 |
| Title |
Activation of TGF-beta pathway by areca nut constituents: A possible cause of Oral submucous fibrosis. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To understand the role of areca nut constituents in manifestation of Oral submucous fibrosis, we studied gene expression profile in epithelial cells following areca nut water extract treatment. A comaprison with TGF-beta induced gene expression changes were performed as epithelial cells were predicted to be source of TGF-beta.
|
| |
|
| Overall design |
Control Vs Areca nut 5 ug/ml water extract (5H) (2), Contro Vs TGF-beta (2), Control Vs ALK5 (TbetaRI inhibitor) (2), Control Vs 5H + ALK5 inhibitor (2). (2)- Biological duplicates.
|
| |
|
| Contributor(s) |
Khan I, Kumar N, Narra S, Kondaiah P |
| Citation(s) |
23284772 |
| Submission date |
May 24, 2012 |
| Last update date |
Feb 22, 2018 |
| Contact name |
Neeraj KUMAR |
| E-mail(s) |
neerajrana14@gmail.com, paturu@mrdg.iisc.ernet.in
|
| Organization name |
Indian Institute of Science Bangalore
|
| Department |
MRDG
|
| Lab |
Prof. P Kondaiah lab
|
| Street address |
Indian Institute of Science Bangalore
|
| City |
Bangalore |
| ZIP/Postal code |
560 012 |
| Country |
India |
| |
|
| Platforms (1) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA167510 |
Less...
More...