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| Status |
Public on Jan 16, 2013 |
| Title |
Expression analysis of 13 squamous cell carcinomas arising in the vulva |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The genome of 14 vulvar SCC was analyzed by aCGH and microarray to identify common imbalances present in the tumors as well as which genes were deregulated. Overall there was a good concordance between the imbalances scored by aCGH and the level of gene expression found by microarray, i.e., the genes located in gained regions were overexpressed while those located in lost regions were found down-regulated.
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| |
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| Overall design |
The whole-gene expression profile of 14 SCC of the vulva was compared to 5 normal vulvar samples to identify genes that were deregulated in the tumors genome.
Vulvar hyperplasia 03-48 not further analyzed and not included in the normalized data but included in the non-normalized data
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| |
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| Contributor(s) |
Micci F, Heim S |
| Citation(s) |
23404381 |
| Submission date |
May 24, 2012 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Francesca Micci |
| E-mail(s) |
francesca.micci@medisin.uio.no
|
| Organization name |
Oslo Universitetssykehus
|
| Department |
Institute for medical informatics
|
| Lab |
cancer cytogenetics
|
| Street address |
Ullernchausseen 70
|
| City |
oslo |
| ZIP/Postal code |
0310 |
| Country |
Norway |
| |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (18)
|
| GSM937045 |
SCC of the vulva 02-1060 expression |
| GSM937046 |
SCC of the vulva 02-1171 expression |
| GSM937047 |
SCC of the vulva 03-830 expression |
| GSM937048 |
SCC of the vulva 03-1011 expression |
| GSM937049 |
SCC of the vulva 03-1088 expression |
| GSM937050 |
SCC of the vulva 06-19 expression |
| GSM937051 |
SCC of the vulva 06-125 expression |
| GSM937052 |
SCC of the vulva 06-709 expression |
| GSM937053 |
SCC of the vulva 09-733 expression |
| GSM937054 |
SCC of the vulva 09-818 expression |
| GSM937055 |
vulvar normal tissue 1102-0370 expression |
| GSM937056 |
vulvar normal tissue 1102-0405 expression |
| GSM937057 |
vulvar normal tissue 1102-0395 expression |
| GSM937058 |
vulvar normal tissue 1102-0325 expression |
| GSM937059 |
vulvar normal tissue 1102-0354 expression |
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| This SubSeries is part of SuperSeries: |
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| Relations |
| BioProject |
PRJNA167467 |
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