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Series GSE38737 Query DataSets for GSE38737
Status Public on Apr 22, 2013
Title Genome-wide expression profiling analysis of a SMC6 mutant mouse model
Organism Mus musculus
Experiment type Expression profiling by array
Summary The function of the SMC5-6 complex is less clear, but it has an important role in a variety of different DNA repair processes and in resolving recombination structures. Interestingly mutation at a highly conserved residue (Ser994) in the ATP hydrolysis motif in the SMC6 C-terminal domain, resulted in mice with a mild phenotype.
 
Overall design Total RNA obtained from homozygote 4 male mutant mice was compared to 2-4 wild type or 2 heterozygote controls.
 
Contributor(s) Beckers J, Horsch M
Citation(s) 23518413
Submission date Jun 15, 2012
Last update date Jun 14, 2018
Contact name Martin Irmler
Organization name Helmholtz Zentrum M√ľnchen GmbH
Department Institute of Experimental Genetics
Lab Gene Regulation & Epigenetics
Street address Ingolstaedter Landstrasse 1
City Neuherberg
State/province Bayern
ZIP/Postal code 85764
Country Germany
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (24)
GSM948840 testis_wt_replicate1
GSM948841 testis_wt_replicate2
GSM948842 testis_wt_replicate3
Relations
BioProject PRJNA168573

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE38737_RAW.tar 3.1 Mb (http)(custom) TAR
GSE38737_non-normalized.txt.gz 4.0 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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