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| Status |
Public on Jul 19, 2012 |
| Title |
Regulatory T cell (T reg) function in HIV exposed seronegative (ESN) individuals |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
T reg frequency, activation and function was studied in ESN individuals. Between the subjects with a HIV-specific T cell response, we identified two groups, one, where the T regs were able to suppress T cell proliferation and one where they lacked this capability. Sorted T regs from this two groups were analysed for their expression pattern.
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| |
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| Overall design |
Nineteen samples with CD4+ T cell response were identified, in 11 of which Tregs were unable to suppress. Due to a low number of sorted cells, samples were run only one time.
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| Contributor(s) |
Pattacini L, Delrow JJ, McElrath MJ, Baeten J, Lund JM |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 18, 2012 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Laura Pattacini |
| E-mail(s) |
lpattaci@fhcrc.org
|
| Phone |
2066672269
|
| Organization name |
Fred Hutchinson Cancer Research Center
|
| Department |
VIDD
|
| Lab |
Lund Lab
|
| Street address |
1100 Fairview Ave N
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (23)
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| Relations |
| BioProject |
PRJNA168648 |
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