|
| Status |
Public on Jun 21, 2012 |
| Title |
Differential gene expression profiling of cultured neu-transformed versus spontaneously-transformed rat cholangiocytes and of corresponding cholangiocarcinomas |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
Characterization of preclinical models of intrahepatic cholangiocarcinoma progression that reliably recapitulate altered molecular features of the human disease. Here, we performed comprehensive gene expression profiling of cholangiocarcinoma tumors arising from bile duct inoculation of different grade malignant rat cholangiocytes.
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| |
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| Overall design |
Tumors arising from bile duct inoculation of spontaneously-transformed low grade malignant rat BDE1 cholangiocytes (BDEsp cells) compared to tumors arising from the inoculation of high grade malignant erbB-2/neu- transformed BDE1 cholangiocytes (BDEneu cells) into the livers of syngeneic rats.
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| |
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| Contributor(s) |
Sirica A, Dumur CI, Campbell D, Oyesanya R |
| Citation(s) |
20816680 |
| Submission date |
Jun 20, 2012 |
| Last update date |
Jul 31, 2017 |
| Contact name |
Catherine Dumur |
| Organization name |
Sonic Healthcare USA
|
| Department |
Anatomic Pathology
|
| Lab |
Bernhardt
|
| Street address |
5008 Mustang Rd
|
| City |
Jacksonville |
| State/province |
FL |
| ZIP/Postal code |
32216 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
|
| Samples (26)
|
|
| Relations |
| BioProject |
PRJNA169089 |
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