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| Status |
Public on Jul 10, 2012 |
| Title |
GEP data from BCWM.1 cells treated with LNA antimiR-155 or scramble control |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
microRNA-155 acts as an oncogenic miRNA in B-cell lymphoproliferative disorders including Waldenstrom Macroglobulinemia (WM) and Chronic Lymphocytic Leukemia (CLL).
we used an 8-mer LNA (locked nucleic acid) phosphorothioate oligonucleotide targeting the seed region of miR-155 to effectively antagonize in vitro tumor growth in WM.
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| Overall design |
We performed gene expression profiling (GEP) analysis on BCWM.1 cells after treatment with LNA antimiR-155 or scramble control for 48 hours.
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| Contributor(s) |
Zhang Y, Ghobrial IM |
| Citation(s) |
22797699 |
| Submission date |
Jul 09, 2012 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Yong Zhang |
| E-mail(s) |
yong_zhang@dfci.harvard.edu
|
| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Medical Oncology
|
| Street address |
450 Brookline Ave
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA170178 |
