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Series GSE39194 Query DataSets for GSE39194
Status Public on Sep 15, 2012
Title Effect of ATF4 overexpression on mRNA levels in differentiated C2C12 myotubes.
Organism Mus musculus
Experiment type Expression profiling by array
Summary ATF4 is a bZIP transcription factor that that promotes skeletal muscle atrophy. The goal of these studies was to determine the effects of ATF4 overexpression on mRNA levels in differentiated C2C12 myotubes.
For additional details see Ebert et al, Stress-Induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy. JBC epub. June 12,2012
 
Overall design C2C12 myotubes were infected with adenovirus co-expressing eGFP and ATF4-FLAG. Control myotubes were infected with adenovirus co-expressing eGFP and a transcriptionally inactive ATF4 construct (ATF4∆bZIP).
 
Contributor(s) Ebert SM, Adams CM
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Submission date Jul 09, 2012
Last update date Mar 06, 2018
Contact name Christopher Adams
Organization name University of Iowa
Street address 540G EMRB, 200 Hawkins Drive
City Iowa City
State/province IA
ZIP/Postal code 52242
Country USA
 
Platforms (1)
GPL6096 [MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version]
Samples (6)
GSM957773 Control sample 1
GSM957774 Control sample 2
GSM957775 Control sample 3
Relations
BioProject PRJNA170207

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39194_RAW.tar 134.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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