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Status |
Public on Sep 15, 2012 |
Title |
Effect of ATF4 overexpression on mRNA levels in differentiated C2C12 myotubes. |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
ATF4 is a bZIP transcription factor that that promotes skeletal muscle atrophy. The goal of these studies was to determine the effects of ATF4 overexpression on mRNA levels in differentiated C2C12 myotubes. For additional details see Ebert et al, Stress-Induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy. JBC epub. June 12,2012
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Overall design |
C2C12 myotubes were infected with adenovirus co-expressing eGFP and ATF4-FLAG. Control myotubes were infected with adenovirus co-expressing eGFP and a transcriptionally inactive ATF4 construct (ATF4∆bZIP).
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Contributor(s) |
Ebert SM, Adams CM |
Citation missing |
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Submission date |
Jul 09, 2012 |
Last update date |
Mar 06, 2018 |
Contact name |
Christopher Adams |
Organization name |
University of Iowa
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Street address |
540G EMRB, 200 Hawkins Drive
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City |
Iowa City |
State/province |
IA |
ZIP/Postal code |
52242 |
Country |
USA |
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Platforms (1) |
GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
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Samples (6)
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Relations |
BioProject |
PRJNA170207 |