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| Status |
Public on Sep 15, 2012 |
| Title |
Effect of denervation on mouse skeletal muscle mRNA levels. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Muscle denervation causes skeletal muscle atrophy. The goal of these studies was to determine the effects of denervation on skeletal muscle mRNA levels in C57BL/6 mice.
For additional details see Ebert et al, Stress-Induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy. JBC epub. June 12, 2012.
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| Overall design |
Left sciatic nerves of C57BL/6 mice were transected. Seven days later bilateral tibialis anterior muscles were harvested. mRNA levels in denervated muscles were normalized to levels in contralateral innervated muscles.
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| Contributor(s) |
Ebert SM, Adams CM |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jul 09, 2012 |
| Last update date |
Mar 06, 2018 |
| Contact name |
Christopher Adams |
| Organization name |
University of Iowa
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| Street address |
540G EMRB, 200 Hawkins Drive
|
| City |
Iowa City |
| State/province |
IA |
| ZIP/Postal code |
52242 |
| Country |
USA |
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| Platforms (1) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA170208 |
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