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Series GSE39223 Query DataSets for GSE39223
Status Public on Apr 25, 2014
Title Regulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [HG-U133_Plus_2]
Organism Homo sapiens
Experiment type Expression profiling by array
Summary U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ), when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene profile changes compared to control. These include the genes from human tumour cells and mouse host stroma cells.
Overall design 3 control samples, 3 dibenzazepine-treated samples, 3 bevacizumab-treated samples
Contributor(s) Buffa F, Harris A
Citation(s) 23871637
Submission date Jul 10, 2012
Last update date Mar 25, 2019
Contact name Francesca Buffa
Organization name University of Oxford
Street address The Weatherall Institute of Molecular Medicine
City Oxford
ZIP/Postal code OX3 9DS
Country United Kingdom
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (9)
GSM958322 U87-EV human glioblastoma xenograft - Control - 1 [HG-U133_Plus_2]
GSM958323 U87-EV human glioblastoma xenograft - Control - 2 [HG-U133_Plus_2]
GSM958324 U87-EV human glioblastoma xenograft - Control - 3 [HG-U133_Plus_2]
BioProject PRJNA170248

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39223_RAW.tar 45.2 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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