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Series GSE39413 Query DataSets for GSE39413
Status Public on Apr 25, 2014
Title Regulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [Mouse430_2]
Platform organism Mus musculus
Sample organism Homo sapiens
Experiment type Expression profiling by array
Summary U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ) when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene profile changes compared to control. These include the genes from human tumour cells and mouse host stroma cells.
 
Overall design 5 control, 5 dibenzazepine-treated, and 4 bevacizumab-treated samples
 
Contributor(s) Buffa F, Harris A
Citation(s) 23871637
Submission date Jul 17, 2012
Last update date Feb 11, 2019
Contact name Francesca Buffa
E-mail(s) francesca.buffa@imm.ox.ac.uk
Organization name University of Oxford
Street address The Weatherall Institute of Molecular Medicine
City Oxford
ZIP/Postal code OX3 9DS
Country United Kingdom
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (14)
GSM967852 U87-EV human glioblastoma xenograft - Control 1
GSM967853 U87-EV human glioblastoma xenograft - Control 2
GSM967854 U87-EV human glioblastoma xenograft - Control 3
Relations
BioProject PRJNA170839

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39413_RAW.tar 81.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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