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Series GSE39467 Query DataSets for GSE39467
Status Public on Nov 01, 2017
Title Profiling the target genes for MTA2 and EZH2 in HCT116
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Using ChIP-seq technology, we tried to find out the whole genome targets for MTA2 and EZH2 in human colon cancer cells. More than 1700 genes were defined as the target of both MTA2 and EZH2, implying that MTA2 and EZH2 coordinate to participate in regulating a common set of target genes. Our results demonstrate a coordinated histone regulating model of gene transcriptional repression.
 
Overall design ChIP-seqs using antibodies against MTA2, EZH2 and IgG.
 
Contributor(s) Zhu W
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jul 18, 2012
Last update date May 15, 2019
Contact name Tingting Li
E-mail(s) litt@hsc.pku.edu.cn
Phone +86-10-82801585
Organization name Peking University
Department Medical informatics
Street address 38 Xueyuan Rd
City Beijing
ZIP/Postal code 100191
Country China
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (4)
GSM969795 MTA2_ChIPSeq
GSM969796 EZH2_ChIPSeq
GSM969797 IgG_ChIPSeq
Relations
BioProject PRJNA170925
SRA SRP014459

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39467_RAW.tar 696.4 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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