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Series GSE39842 Query DataSets for GSE39842
Status Public on Jan 15, 2013
Title Hypoxia induces myocardial regeneration in zebrafish
Organism Danio rerio
Experiment type Expression profiling by array
Summary Conditional expression of dominant-negative HIF1a in zebrafish cardiomyocytes severely inhibits heart regeneration. To understand more about the mechanism, we performed microarray analysis of wildtype regenerating zebrafish and dnHIF1a regenerating zebrafish to determine which genes are regulated by hypoxia/HIF1a.
Overall design We amputated both wildtype and dnHIF1a zebrafish and allowed them to regenerate for 7 days, then compared their transcriptomic profile with unamputated wildtype and dnHIF1a zebrafish, respectively.
Contributor(s) Ispizua Belmonte JC, Jopling C
Citation(s) 23151342
Submission date Aug 02, 2012
Last update date Jan 25, 2018
Contact name Chris Jopling
Phone +33 434359253
Organization name Institut de Génomique Fonctionnelle
Department Physiologie
Lab Molecular mechansims of regeneration
Street address 141 rue de la Cardonille
City Montpellier
ZIP/Postal code 34094
Country France
Platforms (1)
GPL1319 [Zebrafish] Affymetrix Zebrafish Genome Array
Samples (12)
GSM980273 Unamputated dnHIF1a-expressing adult zebrafish, sample 1
GSM980274 Unamputated dnHIF1a-expressing adult zebrafish, sample 2
GSM980275 Unamputated dnHIF1a-expressing adult zebrafish, sample 3
BioProject PRJNA171838

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MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39842_RAW.tar 22.7 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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