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Series GSE40240 Query DataSets for GSE40240
Status Public on Sep 20, 2013
Title Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (ER and DR)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To determine differential gene expression in peripheral blood of asthmatic individuals undergoing allergen inhalation challenge between early responders (ERs) and dual responders (DRs) following allergen inhalation challenge
Overall design Blood was collected immediately prior to, and two hours after challenge
The change in gene expression (post expression minus pre expression) in ERs was compared with the change in gene expression in DRs using age and sex as covariates
Preprocessing and probeset filtering were applied to the entire dataset (28 CEL files) using the Factor Analysis for Robust MicroArray Summarization (farms) package in R
The Linear Models for MicroArrays (limma) package was used to determine differential gene expression using a Benjamini Hochberg FDR of 10%.
Contributor(s) Singh A, Yamamoto M, Kam SH, Ruan J, Gauvreau GM, O'Byrne PM, FitzGerald JM, Boulet L, Wojewodka G, Kanagaratham C, De Sanctis JB, Radzioch D, Tebbutt SJ
Citation(s) 23844124
Submission date Aug 20, 2012
Last update date Jul 26, 2018
Contact name Scott Tebbutt
Organization name University of British Columbia
Department Medicine
Lab James Hogg Research Centre
Street address Room 166, 1081 Burrard Street
City Vancouver
State/province BC
ZIP/Postal code V6Z 1Y6
Country Canada
Platforms (1)
GPL6244 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Samples (28)
GSM989153 Subject LST003, biological rep1
GSM989154 Subject LST014, biological rep1
GSM989155 Subject LST016, biological rep1
BioProject PRJNA173271

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40240_RAW.tar 106.3 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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