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| Status |
Public on Sep 30, 2012 |
| Title |
The effect on gene expression of Smchd1 deletion in pre-B cells from E17.5 Eµ-Myc embryos |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Smchd1 appears to act as a tumour suppressor in the Eµ-Myc mouse B cell lymphoma model. We find a small number of gene expression differences at E17.5 in the pre-B cells, before phenotypic differences are observed.
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| Overall design |
The microarrays compared Smchd1 null and Smchd1 wildtype E17.5 preB cell samples. All samples are on the C57BL/6 background and carry the Eµ-Myc transgene, and the Smchd1 null samples are additionally homozygous for a Smchd1 genetrap allele.
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| Contributor(s) |
Leong HS, Hu Y, Blewitt ME, Smyth GK |
| Citation(s) |
23269277 |
| Submission date |
Sep 14, 2012 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Gordon K Smyth |
| E-mail(s) |
smyth@wehi.edu.au
|
| Phone |
(+61 3) 9345 2326
|
| Fax |
(+61 3) 9347 0852
|
| URL |
http://www.wehi.edu.au
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| Organization name |
Walter and Eliza Hall Institute of Medical Research
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| Department |
Bioinformatics
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| Lab |
Smyth
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| Street address |
1G Royal Pde
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| City |
Parkville |
| State/province |
Vic |
| ZIP/Postal code |
3052 |
| Country |
Australia |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE40992 |
The effect on gene expression of Smchd1 deletion in various cell types |
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| Relations |
| BioProject |
PRJNA175421 |
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