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Series GSE40982 Query DataSets for GSE40982
Status Public on Jul 03, 2013
Title Gene expression in mouse retinas with cone cyclic nucleotide gated channel deficiencies
Organism Mus musculus
Experiment type Expression profiling by array
Summary The cone photoreceptor cyclic nucleotide-gated (CNG) channel is essential for central and color vision and visual acuity. Mutations in the channel subunits CNGA3 and CNGB3 are associated with achromatopsia and cone dystrophy. We investigated the gene expression profiles in mouse retina with CNG channel deficiency on a cone-dominant background, i.e., CNGA3-/-/Nrl-/- and CNGB3-/-/Nrl-/- mice, relative to Nrl-/- mice.
 
Overall design Total RNA was isolated from 2 retinas per animal (CNGA3-/-/Nrl-/-, CNGB3-/-/Nrl-/-, and Nrl-/- mice). The background strain for these mutations was C57bl/6.
 
Contributor(s) Frank B, Ding X
Citation(s) 23740940
Submission date Sep 19, 2012
Last update date Jun 14, 2018
Contact name Bart Frank
E-mail(s) frank@omrf.org
Organization name OMRF
Street address 825 NE 13 St
City Oklahoma City
State/province OK
ZIP/Postal code 73103
Country USA
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (15)
GSM1006347 CNGA3 replicate-1
GSM1006348 CNGA3 replicate-2
GSM1006349 Nrl replicate-1
Relations
BioProject PRJNA175488

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40982_RAW.tar 3.1 Mb (http)(custom) TAR
GSE40982_non-normalized.txt.gz 2.3 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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