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Series GSE41018 Query DataSets for GSE41018
Status Public on Jul 29, 2013
Title Rapamycin extends life span, but has limited effects on aging in mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary Rapamycin extends life span in mice, but it remains unclear if this compound also delays mammalian aging. Here, we present results from a comprehensive large-scale assessment of a wide rage of structural and functional aging phenotypes in mice. Rapamycin extended life span but showed few effects on a large number of systemic aging phenotypes, suggesting that rapamycin's effects on aging are largely limited to the regulation of age-related mortality and carcinogenesis.
 
Overall design Total RNA obtained from 2-4 male mice of each analysed group (25 weeks old controls, 25 month old controls, 25 month old rapamycin treated)
 
Contributor(s) Beckers J, Horsch M
Citation(s) 23863708
Submission date Sep 20, 2012
Last update date Jun 14, 2018
Contact name Martin Irmler
Organization name Helmholtz Zentrum M√ľnchen GmbH
Department Institute of Experimental Genetics
Lab Gene Regulation & Epigenetics
Street address Ingolstaedter Landstrasse 1
City Neuherberg
State/province Bayern
ZIP/Postal code 85764
Country Germany
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (30)
GSM1006829 kidney_y control_rep1
GSM1006830 kidney_y control_rep2
GSM1006831 kidney_treated_rep1
Relations
BioProject PRJNA175551

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE41018.txt.gz 179 b (ftp)(http) TXT
GSE41018_RAW.tar 3.1 Mb (http)(custom) TAR
GSE41018_non-normalized.txt.gz 4.5 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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