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| Status |
Public on Feb 01, 2006 |
| Title |
training induced gene expression in arrhythmogenic plakogloin (+/-) mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Endurance training accelerated development of right ventricular dysfunction and arrhythmias in plakoglobin+/- mice. Histology and electron microscopy did not identify right ventricular abnormalities. To identify differences in the transcriptional response to training gene expression profiling was performed.
Keywords: expression response of plakoglobin (+/-) to training
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| Overall design |
Gene expressson analyses were performed in 5 pairs of plakoglobin (+/-) mice and their wildtype littermates. Four pairs of trained mice and one pair of old untrained mice were studied. Training induced expression of several hypertrophy associated genes such as ANP but no differences between the trained plakoglobin (+/-) mice and wt mice was seen.
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| Contributor(s) |
Witt H, Ungethuem U, Kirchhof P, Fabritz L, Zwiener M, Ruiz P |
| Citation(s) |
17030684 |
| Submission date |
Jan 30, 2006 |
| Last update date |
Jan 08, 2019 |
| Contact name |
Henning Witt |
| E-mail(s) |
witt@molgen.mpg.de
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| Phone |
++49-30-450578727
|
| Organization name |
Max Planck Institute for Molecular Genetics
|
| Department |
Hans Lehrach
|
| Lab |
Patricia Ruiz
|
| Street address |
Ihnestrasse 65
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| City |
Berlin |
| ZIP/Postal code |
14195 |
| Country |
Germany |
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| Platforms (1) |
| GPL339 |
[MOE430A] Affymetrix Mouse Expression 430A Array |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA94915 |
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