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| Status |
Public on Jan 06, 2013 |
| Title |
Early limb bud transcriptome analysis between anterior and posterior domain |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Shh signal mediated by Gli family of transcription factors regulates digit growth and patterning in early limb development. Shh expression in the posterior margin of the limb bud defines the zone of polarizing activity. However, much less is know about downstream targets that mediate Shh signal functions. In this dataset, we include the expression data obtained from dissected anterior and posterior halves of mouse limb bud respectively. These data are used to obtain 889 transcripts that were upregulated 1.3 fold or more in the posterior limb bud, and 1189 transcripts that were enriched in the anterior limb bud at 1.3 fold or more.
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| Overall design |
Two samples were analyzed. We generate pairwise comparisons between anterior and posterior limb tissues. Genes with a fold-change ≥1.3 were selected.
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| Contributor(s) |
Liu J, Chiang C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 18, 2012 |
| Last update date |
Mar 06, 2018 |
| Contact name |
jiang liu |
| Organization name |
vanderbilt university
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| Department |
cell and dvelopmental biology
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| Lab |
chin chiang
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| Street address |
465 21st ave south, MRB3 RM4114
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| City |
Nashville |
| State/province |
TN |
| ZIP/Postal code |
37232 |
| Country |
USA |
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| Platforms (1) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA177947 |
