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Series GSE42090 Query DataSets for GSE42090
Status Public on Jun 01, 2013
Title The innate and adaptive immune response to BCG stimulation in splenocytes taken from C57BL/6 mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary The aim of this experiment was to investigate differential gene expression in splenocytes stimulated with BCG from naïve and BCG vaccinated mice. The differences between naïve and BCG vaccinated mice might indicate the mechanisms by which BCG vaccination confers an enhanced ability of splenocytes from BCG vaccinated mice to inhibit growth of BCG in splenocyte cultures as compared with splenocytes from naive animals.
 
Overall design Splenocytes from 4 naïve and 4 BCG vaccinated female C57bl/6 mice were cultured for 12 hours with BCG (MOI 1:1) or without (unstimulated control). Each animal had a stimulated and an unstimulated sample hybridised to a beadchip.
 
Contributor(s) Marsay L, Fletcher HE, Kostov M, McShane H
Citation(s) 23726784
Submission date Nov 06, 2012
Last update date Jun 14, 2018
Contact name leanne marsay
E-mail(s) Leanne.marsay@ndm.ox.ac.uk
Phone 01865 857445
Organization name University of Oxford
Department Nuffield department
Lab Jenner Institute
Street address roosevelt drive
City Oxford
ZIP/Postal code OX4 3TU
Country United Kingdom
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (16)
GSM1032271 Naïve_mouse1_unstim
GSM1032272 Naïve_mouse3_unstim
GSM1032273 BCG_mouse2_BCGstim
Relations
BioProject PRJNA179104

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE42090_RAW.tar 3.1 Mb (http)(custom) TAR
GSE42090_non-normalized_data.txt.gz 2.6 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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