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Series GSE42187 Query DataSets for GSE42187
Status Public on Sep 17, 2013
Title Gene expression profile in melanomas from Pdk1-inactivated BrafV600E::Pten-/- mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary Gene expression profiling was performed to access the changes in gene expression in melanomas from Pdk1-inactivated Brafv600E::Pten-/- mice. The expression profiles of the BrafV600E::Pten-/-::Pdk1-/- were compared to the BrafV600E::Pten-/-::Pdk+/+ genotypes. The analysis has identified several important signaling pathways in Pdk1-dependent melanomagenesis.
 
Overall design Melanoma tumors from the BrafV600E::Pten-/-::Pdk1+/+ and BrafV600E::Pten-/-::Pdk1-/- genotypes were harvested and mRNA from each group was pooled to enable four biologically replicates analysis.
 
Contributor(s) Scortegagna M, Li JL, Ronai ZA
Citation(s) 24037523
Submission date Nov 09, 2012
Last update date Jun 14, 2018
Contact name Jian-Liang Li
Organization name NIEHS
Street address 111 TW Alexander Dr
City Durham
State/province NC
ZIP/Postal code 27709
Country USA
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (8)
GSM1034539 Tumor-WT-rep1
GSM1034540 Tumor-WT-rep2
GSM1034541 Tumor-WT-rep3
Relations
BioProject PRJNA179261

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE42187_RAW.tar 3.1 Mb (http)(custom) TAR
GSE42187_non_normalized.txt.gz 1.3 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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