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Series GSE42534 Query DataSets for GSE42534
Status Public on Jun 01, 2013
Title Genome-wide analysis of the effects of propranolol on angiosarcoma tumor cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary Analysis of the effects of 4 hr and 24 hr propranolol treatment on gene expression of SVR mouse angiosarcoma cells. The hypothesis tested in the present study was that inhibiton of beta adrenergic receptor signaling could ablate the oncogenic properties of angiosarcoma cells. Results provide important information of the response of angiosarcoma cells to ablated beta adrenergic receptor signaling.
Overall design The total RNA was obtained from mouse angiosarcoma cells cultured in monolayer at 0, 4, and 24 hrs of 50 micromolar propranolol treatment. Illumina microarrays were performed to determine the whole genome expression changes following treatment.
Contributor(s) Bryan BA, Mitchell DD
Citation(s) 23555867
Submission date Nov 27, 2012
Last update date Jun 14, 2018
Contact name Brad Allen Bryan
Organization name Texas Tech University Health Sciences Center
Department Biomedical Sciences
Street address 5001 El Paso Drive
City El Paso
State/province Texas
ZIP/Postal code 79905
Country USA
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (9)
GSM1044352 SVR, sham, 0h (rep 1)
GSM1044353 SVR, sham, 0h (rep 2)
GSM1044354 SVR, sham, 0h (rep 3)
BioProject PRJNA182219

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE42534_RAW.tar 3.1 Mb (http)(custom) TAR
GSE42534_non-normalized.txt.gz 2.7 Mb (ftp)(http) TXT
GSE42534_normalized.txt.gz 2.7 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table
Processed data are available on Series record

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