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| Status |
Public on Dec 01, 2012 |
| Title |
EID1 knochdown by small RNA induces the large-scale conversion of adipose-derived mesenchymal stem cells into hematopoietic stem cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Comparison of expression profiles in adipose derived MSCs (AD-MSCs) without or with transfection of siR-EID1 and shR-EID1 and cord blood-derived HSCs (CB-HSCs). After MSCs were transfected with sRNA-EID1, they could be converted into HSCs. The goal was to determine possible molecular mechanisms of MSC transdetermination.
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| Overall design |
Two-condition experiments: AD-MSCs vs CB-HSCs, and AD-MSCs transfected with the combination of siR-EID1 and shR-EID1 vs AD-MSCs transfected with shR-EID1.
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| Contributor(s) |
Yin JQ, Wang S, Yin H, Xu R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 30, 2012 |
| Last update date |
Jan 23, 2019 |
| Contact name |
James Yin |
| E-mail(s) |
jamesyin2010@126.com
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| Phone |
86-10-84008003
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| Fax |
86-10-84008003
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| Organization name |
The military general hospital of Beijing PLA
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| Street address |
Dongcheng District, 5 Nanmengcang
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| City |
Beijing |
| ZIP/Postal code |
100700 |
| Country |
China |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA182511 |
