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Series GSE43471 Query DataSets for GSE43471
Status Public on Jan 15, 2013
Title Gene expression changes in adipose tissue with diet- and/or exercise-induced weight loss
Organism Homo sapiens
Experiment type Expression profiling by array
Summary An ancillary study within a randomized trial of diet, exercise, or combined diet+exercise vs. control among overweight/obese postmenopausal women. Subcutaneous adipose-tissue biopsies were performed at baseline and after 6 months and changes in adipose-tissue gene expression were determined by microarray with an emphasis on pre-specified candidate pathways, as well as by unsupervised clustering. Analyses were conducted first by randomization group, and then by degree of weight change at 6-months in all women combined.
 
Overall design Total RNA was obtained from subcutaneous adipose tissue biopsies at baseline and 6 months. A total of 47 women were biopsied and one replicate participant was included for a total of 96 samples.
 
Contributor(s) Campbell KL, Foster-Schubert KE, Makar KW, Kratz M, Hagman D, Schur EA, Habermann N, Horton M, Abbenhardt C, Kuan L, Xiao L, Davison J, Morgan M, Wang C, Duggan C, McTiernan A, Ulrich CM
Citation(s) 23341572
Submission date Jan 14, 2013
Last update date Aug 16, 2018
Contact name Karen Weber Makar
E-mail(s) kmakar@fhcrc.org
Organization name Fred Hutchinson Cancer Research Center
Street address 1100 Fairview Ave N Po box 19024
City Seattle
State/province WA
ZIP/Postal code 98109
Country USA
 
Platforms (1)
GPL6947 Illumina HumanHT-12 V3.0 expression beadchip
Samples (96)
GSM1063183 subcutaneous adipose tissue needle biopsy Participant 1 control group baseline visit (technical rep1)
GSM1063184 subcutaneous adipose tissue needle biopsy Participant 1 control group 6 month visit (technical rep1)
GSM1063185 subcutaneous adipose tissue needle biopsy Participant 2 diet group baseline visit
Relations
BioProject PRJNA186511

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE43471_RAW.tar 6.2 Mb (http)(custom) TAR
GSE43471_non_normalized.txt.gz 54.3 Mb (ftp)(http) TXT
Processed data included within Sample table
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