|
| Status |
Public on Jan 15, 2013 |
| Title |
Gene expression profiling of dsDNA90 or ssDNA90 stimulated Mouse Embryonic Fibroblasts |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression analysis of wild type, STING knock-out and STAT1 knock-out Mouse Embryonic Fibroblasts (MEFs) stimulated with 90-mer dsDNA or 90-mer ssDNA. Genes whose expression that are affected by cytosolic DNA in a STING dependent manner will be identified and signaling pathways regulated by STING will be elucidated.
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| |
|
| Overall design |
Primary MEFs were mock treated or transfected with dsDNA90 or ssDNA90 for 3 hours. Total RNA was then extracted for array analysis.
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| |
|
| Contributor(s) |
Barber G, Xia T |
| Citation(s) |
23478444 |
| Submission date |
Jan 14, 2013 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Tianli Xia |
| E-mail(s) |
txia@med.miami.edu
|
| Organization name |
University of Miami
|
| Street address |
1550 NW 10th Ave
|
| City |
Miami |
| State/province |
FL |
| ZIP/Postal code |
33136 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
|
| Samples (20)
|
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| This SubSeries is part of SuperSeries: |
| GSE43482 |
Cytosolic DNA stimulated gene regulation |
|
| Relations |
| BioProject |
PRJNA186544 |
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