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Series GSE43495 Query DataSets for GSE43495
Status Public on Sep 09, 2013
Title Expression data of mammary epithelial cells during the epithelial-mesenchymal transition
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The EMT program allows epithelial cells to become endowed with motility, invasiveness and stem cell traits. We investigated difference in signaling networks that are differentially utilized in EMTed and non-EMTed cells, thereby identifying therapeutic targets that are unique to EMT/cancer stem cells.
 
Overall design We expressed the EMT transcription factors, Twist, Snail and Slug in HMLE human mammary epithelial cells, and compared their gene expression with parental cells. We identified kinases that are more differentially regulated between the epithelial and mesenchymal cell state.
 
Contributor(s) Tam WL
Citation(s) 24029232
Submission date Jan 15, 2013
Last update date Mar 20, 2017
Contact name Wai Leong Tam
E-mail(s) tamwl@wi.mit.edu
Organization name Whitehead Institute
Street address 9 Cambridge Center
City Cambridge
ZIP/Postal code 02142
Country USA
 
Platforms (1)
GPL6883 Illumina HumanRef-8 v3.0 expression beadchip
Samples (15)
GSM1064152 HMLE untreated_a
GSM1064153 HMLE untreated_b
GSM1064154 HMLE untreated_c
Relations
BioProject PRJNA186603

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE43495_RAW.tar 3.9 Mb (http)(custom) TAR
GSE43495_non-normalized_data.txt.gz 888.3 Kb (ftp)(http) TXT
Processed data included within Sample table

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