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Series GSE4351 Query DataSets for GSE4351
Status Public on Mar 07, 2006
Title Variation in gene expression patterns in follicular lymphoma and the response to rituximab
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Abstract: Analysis of the patterns of gene expression in follicular lymphomas from 24 patients suggested that two groups of tumors might be distinguished. All patients, whose biopsies were obtained before any treatment, were treated with rituximab, a monoclonal antibody directed against the B cell antigen, CD20. Gene expression patterns in the tumors that subsequently failed to respond to rituximab appeared more similar to those of normal lymphoid tissues than to gene expression patterns of tumors from rituximab responders. These findings suggest the possibility that the response of follicular lymphoma to rituximab treatment may be predicted from the gene expression pattern of tumors.

This SuperSeries is composed of the SubSeries listed below.
Overall design Refer to individual Series
Citation(s) 12571354
Submission date Mar 06, 2006
Last update date Dec 28, 2012
Organization Stanford Microarray Database (SMD)
Phone 650-498-6012
Department Stanford University, School of Medicine
Street address 300 Pasteur Drive
City Stanford
State/province CA
ZIP/Postal code 94305
Country USA
Platforms (3)
GPL3113 LC-23
Samples (48)
GSM84697 Normal Spleen (N3)
GSM84698 FL2 PR
GSM84699 Normal Tonsil (N2)
This SuperSeries is composed of the following SubSeries:
GSE3646 Follicular lymphoma and normal lymphoid tissue comparisons
GSE3647 Follicular lymphoma lymph node
BioProject PRJNA94797

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