|
| Status |
Public on May 21, 2015 |
| Title |
Activation of beta-catenin in hepatocellular carcinoma (HCC patients) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
CTNNB1 is the most frequently mutated gene in hepatocellular carcinoma (HCC). However, its clinical relevance remains controversial. We determined an evolutionarily conserved β-catenin signature by comparative analysis of gene expression data from human HCC and a mouse model (GSE43628). We generated gene expression data from the tumors of 88 HCC patients who underwent surgical resection as the primary treatment. We used these gene expression data to develop a new prognostification model for prognosis of HCC after surgery.
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| |
|
| Overall design |
We generated gene expression data from the tumors of 88 HCC patients who underwent surgical resection as the primary treatment.
|
| |
|
| Contributor(s) |
Kim JH, Kang KJ, Lee JS, Park YY |
| Citation(s) |
25661872 |
| Submission date |
Jan 18, 2013 |
| Last update date |
May 02, 2023 |
| Contact name |
Sangbae Kim |
| E-mail(s) |
sangbkim22@gmail.com
|
| Organization name |
Baylor Colleage of Medicine
|
| Department |
HGSC
|
| Street address |
1 Baylor plaza
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (88)
|
|
| Relations |
| BioProject |
PRJNA186849 |
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