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Status |
Public on Jan 10, 2014 |
Title |
Gene expression profiling in cumulus cells (CC) derived from a modified natural and stimulated in vitro fertilization (IVF) procedures |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Cumulus cells surrounding mature oocytes that developed to moruale/blastocyst stage on day 5 of IVF cycle were collected and used for gene expression profiling using Affymetrix Human Gene 1.0 ST Arrays in order to determine differences in gene expression between the modified natural and stimulated in vitro fertilization (IVF) procedures.
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Overall design |
Microarray analysis was made on 8 individual CC samples, derived from 5 patients that first underwent MNIVF, followed by a controlled ovarian hyperstimulation (COH) cycle. As the quality of the isolated RNA derived from 2 of the MNIVF CC samples was not good, these samples were not included in the analysis. Altogether, 3 CC samples from MNIVF and 5 CC samples from COH cycles were included in microarray analysis.
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Contributor(s) |
Burnik Papler T, Fon Tacer K, Devjak R, Juvan P, Virant Klun I, Vrtačnik Bokal E |
Citation(s) |
24221912 |
Submission date |
Jan 23, 2013 |
Last update date |
Jul 26, 2018 |
Contact name |
Peter Juvan |
Phone |
+386 1 543 7595
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Organization name |
Faculty of Medicine, University of Ljubljana
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Department |
Institute of Biochemistry
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Lab |
Center for Functional Genomics and Bio-Chips
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Street address |
Zaloska 4
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City |
Ljubljana |
ZIP/Postal code |
SI-1000 |
Country |
Slovenia |
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Platforms (1) |
GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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Samples (8)
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Relations |
BioProject |
PRJNA187053 |