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Status |
Public on Jan 01, 2014 |
Title |
gene expression Fulminant type 1 diabetes vs classical type 1A diabetes vs healthy controls |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We determined the genes that were differentially expressed between fulminant type 1 diabetes and classical type 1A diabetes or healthy control using gene expression microarray in peripheral blood cells.
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Overall design |
Ten patients with type 1 diabetes (5 fulminant and 5 classical type 1A) and 6 healthy controls were enrolled in this study. All patients had recovered from ketosis or ketoacidosis at disease onset and had been receiving intensive insulin injection therapy for at least 1 month, which means that all patients and healthy controls were free of metabolic derangements at the time of blood sampling. To determine the genes that were differentially expressed among fulminant type 1 diabetes, classical type 1A and healthy controls, a volcano plot analysis (fold change >1.5 and p-value <0.05) was performed.
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Citation(s) |
24177169 |
Submission date |
Feb 13, 2013 |
Last update date |
Jan 23, 2019 |
Contact name |
Shinsuke Nakata |
E-mail(s) |
nakata@endmet.med.osaka-u.ac.jp
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Phone |
81-6-6879-3732
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Fax |
81-6-6879-3739
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Organization name |
Osaka University, Graduate School of Medicine
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Department |
Metabolic Medicine
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Street address |
2-2-B5, Yamadaoka
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City |
Suita |
ZIP/Postal code |
565-0871 |
Country |
Japan |
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Platforms (1) |
GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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Samples (16)
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Relations |
BioProject |
PRJNA189469 |