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Status |
Public on Feb 26, 2013 |
Title |
Human MCF7 cells: Mock control vs. siRNA transfected against calreticulin |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Transcriptional profiling of human MCF7 cells comparing mock control MCF7cells with MCF7cells transfected by siRNA against calreticulin. The latter was shown to be of having significantly decreased expression of calreticulin followed by significant decrease in migrative and invasive potentials of the MCF7 cells. Goal was to determine the effect of calreticulin knockdown on the global gene expression of MCF7 cells.
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Overall design |
Two-condition experiment, Mock control MCF7 cells vs. calreticulin siRNA knockdown MCF7 cells. Biological replicates: 3 mock control replicates, 3 transfected replicates.
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Contributor(s) |
Zamanian M, Veeracumarasivam A, Rosli R |
Citation(s) |
27418879 |
Submission date |
Feb 18, 2013 |
Last update date |
Apr 02, 2020 |
Contact name |
Mohammadreza Zamanian |
E-mail(s) |
zamanzss@gmail.com
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Organization name |
Royan Institute
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Department |
Genetics
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Lab |
Molecular Genetics
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Street address |
Hafez al., Bani Hashem st., Resalat Highway
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City |
Tehran |
State/province |
Tehran |
ZIP/Postal code |
1665659911 |
Country |
Iran |
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Platforms (1) |
GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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Samples (3) |
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Relations |
BioProject |
PRJNA190652 |