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| Status |
Public on Aug 31, 2014 |
| Title |
Expression data of age-specific ovaries in rhesus monkey |
| Organism |
Macaca mulatta |
| Experiment type |
Expression profiling by array
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| Summary |
The biological function of human ovaries declines with increasing age. Moreover, disorders that cause reproductive failure, such as premature ovarian failure (POF), seriously affect the female health and may be related to abnormal gene expression in the ovaries.
The objective of this study was to generate the gene expression proļ¬les of ovaries in rhesus monkeys of different ages, so as to identify age-related changes in the ovaries and understand their significance in various human reproductive problems.
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| Overall design |
Ovaries were obtained from young (Y, 3 to 4 years), middle-age (M, 7 to 8 years) and old (O, 18 to 19 years) monkeys, and each group had 3 monkey replications. Half of ovary from each monkey was isolated mRNA for whole genome gene expression microarray analysis to detect differentially expressed genes, and followed by the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses by using a free web-based Molecular Annotation System 3.0 (MAS 3.0).
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| Contributor(s) |
Wei H, Liu X, Li L, Guo X, Liu L, Zhang S |
| Citation(s) |
26421297 |
| Submission date |
Feb 21, 2013 |
| Last update date |
Jul 31, 2019 |
| Contact name |
hengxi wei |
| E-mail(s) |
weihengxi@scau.edu.cn
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| Organization name |
scau
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| Street address |
No. 483, wushan
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| City |
guangzhou |
| ZIP/Postal code |
510642 |
| Country |
China |
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| Platforms (1) |
| GPL3535 |
[Rhesus] Affymetrix Rhesus Macaque Genome Array |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA190027 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE44533_RAW.tar |
40.3 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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