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Series GSE44941 Query DataSets for GSE44941
Status Public on Dec 31, 2017
Title Cancer-related epigenome changes among induced pluripotent stem cell lines
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To identify hypermethylated genes in induced pluripotent stem cell lines, human embryonic stem cell lines, and non-nucleofected CD34+ CB cells, indicated cell lines were treated with 5-aza-2′-deoxycytidine (DAC) or trichostatin A (TSA), and drug-induced changes in gene expression vs control treatment (PBS) were identified using Agilent two-color arrays, using the experimental methods of Ohm et al. (Cancer Res 70:7662-7673 2010).
 
Overall design Total RNA was harvested from indicated conditions. A single sample of each cell line was used for this analysis.
 
Contributor(s) Pandiyan K, Van Neste L, Park TS, Yu W, Peters A, Reijo-Pera R, Baylin SB, Zambidis ET
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Mar 07, 2013
Last update date Feb 22, 2018
Contact name Elias Thomas Zambidis
Organization name Johns Hopkins School of Medicine
Department Oncology
Street address 733 N. Broadway
City Baltimore
State/province MD
ZIP/Postal code 21205
Country USA
 
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (28)
GSM1094224 DAC-treated H1 human Embryonic Stem Cells, Passage 42 (NIH Code WA01)
GSM1094225 TSA-treated H1 human Embryonic Stem Cells, Passage 42 (NIH Code WA01)
GSM1094226 DAC-treated nonviral 7F Adult fibroblast iPSC clone 6.6 p17
This SubSeries is part of SuperSeries:
GSE82233 Quality of reprogramming to induced pluripotency as a function of reprogramming method
Relations
BioProject PRJNA192592

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE44941_RAW.tar 442.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
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