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Series GSE45256 Query DataSets for GSE45256
Status Public on Mar 19, 2013
Title Genome-wide analysis of gene expression in murine breast fibroblasts from normal tissue, hyperplasia, adenoma and carcinoma (MMTV-PyMT model)
Organism Mus musculus
Experiment type Expression profiling by array
Summary Analysis of differences at gene expression level of hpvE6 immortalized fibroblasts isolated from normal mammary glands and from hyperplasia, adenoma and carcinoma stages using the MMTV-PyMT model (FVB/N background). Analysis demonstrated the activation of specific transcriptional programs in fibroblasts from later stages.
Overall design Total RNA obtained from isolated hpvE6 immortalized fibroblasts from normal mammary gland (NF) and from different stages of tumour development using the MMTV-PyMT murine breast cancer model. Stages were hyperplasia (HpAF), adenoma (AdAF) and carcinoma (CAF). Fibroblasts were seeded in a deformable Matrigel:collagen I matrix and total RNA isolated 72h later.
Contributor(s) Calvo F, Sahai E
Citation(s) 23708000
Submission date Mar 18, 2013
Last update date Jun 14, 2018
Contact name Fernando Calvo
Organization name Cancer Research UK
Department London Research Institute
Lab Tumour Cell Biology
Street address 44 Lincoln's Inn Fields
City London
ZIP/Postal code WC2A 3LY
Country United Kingdom
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (16)
GSM1100176 NF2_ongel_rep1
GSM1100177 NF2_ongel_rep2
GSM1100178 NF3_ongel_rep1
BioProject PRJNA193324

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45256_RAW.tar 3.1 Mb (http)(custom) TAR
GSE45256_non-normalized.txt.gz 2.6 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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