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| Status |
Public on Dec 31, 2014 |
| Title |
In vivo gene expression analysis of C elegans in response to rifampicin |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by array
|
| Summary |
We have discovered rifampicin as a glycation inhibitor, which increases life span in C elegans. In order to understand the mechanism of rifampicin action, microarray analysis was performed to study the changes in gene expression brought about by the drug.
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| Overall design |
Gene expression profile of wild type N2 worms treated with rifampicin w.r.t to control (DMSO treated) worms.Total RNA was isolated from worms on 8th day of adulthoodin presence of FuDr. Two independent biological replicates for each treatment were analyzed.
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| |
|
| Contributor(s) |
Golegaonkar SB, Kulkarni MJ, Mukhopadhyay A |
| Citation(s) |
25720500 |
| Submission date |
Mar 19, 2013 |
| Last update date |
Jul 06, 2016 |
| Contact name |
Arnab Mukhopadhyay |
| E-mail(s) |
arnab@nii.ac.in
|
| Phone |
+91 11 26703885
|
| Organization name |
National Institute of Immunology
|
| Lab |
Molecular Aging Lab
|
| Street address |
Aruna Asaf Ali Marg
|
| City |
New Delhi |
| ZIP/Postal code |
110067 |
| Country |
India |
| |
|
| Platforms (1) |
| GPL200 |
[Celegans] Affymetrix C. elegans Genome Array |
|
| Samples (4)
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| Relations |
| BioProject |
PRJNA193421 |
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