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Series GSE45757 Query DataSets for GSE45757
Status Public on Apr 04, 2013
Title Expression Data from 22 human pancreatic cancer cell lines grown in triplicates +/- MEK inhibitor CI-1040
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.
We used microarrays to find gene expression patterns associated with drug response and also identified genes regulated by the MAP kinase pathway
 
Overall design 22 pancreatic cell lines were grown in culture media containing serum and either treated with vehicle control or CI-1040 for 24 hours
 
Contributor(s) Gysin S, Paquette J, McMahon M
Citation(s) 22833572
Submission date Apr 03, 2013
Last update date Dec 06, 2018
Contact name Stephan Christoph Gysin
E-mail(s) sgysin@cc.ucsf.edu
Organization name UCSF
Department HDFCCC
Lab McCormick
Street address 1450 3rd Street
City San Francisco
State/province California
ZIP/Postal code 94158
Country USA
 
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (141)
GSM1113671 normal human pancreatic ductal epithelial cells specimen 1, replica 1
GSM1113672 normal human pancreatic ductal epithelial cells specimen 1, replica 2
GSM1113673 normal human pancreatic ductal epithelial cells specimen 1, replica 3
This SubSeries is part of SuperSeries:
GSE45765 Expression Data from pancreatic cancer cell lines and orthotopic tumors grown with and without MEK inhibitor
Relations
BioProject PRJNA196177

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45757_RAW.tar 345.6 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file
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